Wide variety of speech pronunciation practice (SPP) systems with different features exist for speech therapy. Finding the effect of these systems on speech learning of children as well as proper features is an important issue for speech therapists. In this study a comprehensive systematic literature review is conducted to find desired features and characteristics for designing an efficient SPP system for children and identify shortcomings of the current SPP systems. We concluded that an appropriate SPP system can increase children’s enthusiasm to participant in therapy sessions and increase their concentration and performance during sessions. Furthermore, we presented the reliable features for designing an effective SPP system and indicated potential positive features based on the shortcomings of the current systems.